Hydrocodone: Difference between revisions
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Latest revision as of 18:42, 15 May 2026
Opioid, Analgesic
Hydrocodone
Vicodin
Experience
No personal reports yet
No clinical reports yet
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Problems
No problems yet. Be the first to suggest one.
+ Add a problemTitration strategies
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Effects
No effects listed yet. Be the first to suggest one.
Interactions
Pharmacogenomic + mechanism interactions
Pharmacogenomic guideline recommendationsCPIC and Dutch Pharmacogenetics Working Group clinical guidelines
CPIC rec 8094288 [Strong]: Use hydrocodone label recommended age- or weight-specific dosing. CPIC pair-level B (CYP2D6, OPRM1, COMT, and Opioids) [PMID 33387367]
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Clinical relevance: does this interaction matter in practice?trivialcritical
Mechanism description, if it needs work:
Is this row worth surfacing?
Your own experience with this combination:
Experience (1 a little, 5 a lot)
Outcome (-100 worst, +100 best)
CPIC rec 8094284 [Optional]: Use hydrocodone label recommended age- or weight-specific dosing. If no response and opioid use is warranted, consider non-codeine or non-tramadol opioid. CPIC pair-level B (CYP2D6, OPRM1, COMT, and Opioids) [PMID 33387367]
Rate this interaction. Reports are anonymous and help curate the page.
Clinical relevance: does this interaction matter in practice?trivialcritical
Mechanism description, if it needs work:
Is this row worth surfacing?
Your own experience with this combination:
Experience (1 a little, 5 a lot)
Outcome (-100 worst, +100 best)
CPIC rec 8094293 [Optional]: Use hydrocodone label recommended age- or weight-specific dosing. If no response and opioid use is warranted, consider non-codeine and non-tramadol opioid. CPIC pair-level B (CYP2D6, OPRM1, COMT, and Opioids) [PMID 33387367]
Rate this interaction. Reports are anonymous and help curate the page.
Clinical relevance: does this interaction matter in practice?trivialcritical
Mechanism description, if it needs work:
Is this row worth surfacing?
Your own experience with this combination:
Experience (1 a little, 5 a lot)
Outcome (-100 worst, +100 best)
CPIC rec 8094298 [No Recommendation]: No recommendation for hydrocodone therapy because of minimal evidence regarding adverse events or analgesia. CPIC pair-level B (CYP2D6, OPRM1, COMT, and Opioids) [PMID 33387367]
Rate this interaction. Reports are anonymous and help curate the page.
Clinical relevance: does this interaction matter in practice?trivialcritical
Mechanism description, if it needs work:
Is this row worth surfacing?
Your own experience with this combination:
Experience (1 a little, 5 a lot)
Outcome (-100 worst, +100 best)
Patient experience
No patient-experience reports yet.
Relevant anecdote
No anecdotes yet. Share a relevant one.
Relevant Literature
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Summary
Classes
Opioid, Analgesic
Common uses
Pharmacy
Pharmacology
Purported mechanism
Mu-opioid receptor agonist