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Drilldown: Medicines

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Medicines > classes : Analgesic or Benzodiazepine or Research material

Use the filters below to narrow your results.

generic:
Codeine (2)
brand:
None (136) · (multiple, generic dominant) (1) · (none, never marketed) (1) · Dalmane (1) · Darvon (1) · Demerol (1) · Dilaudid (1) · Dolophine (1) · Doral (1) · Duragesic (1) · Halcion (1) · Lexotan (1) · Librium (1) · Mogadon (1) · Nubain (1) · Nucynta (1) · O-DSMT (1) · Onfi (1) · Opana (1) · ProSom (1) · Restoril (1) · Rohypnol (1) · Serax (1) · Stadol (1) · Suboxone (1) · Talwin (1) · Tranxene (1) · Versed (1) · Vicodin (1) · Xanax (1)
classes: (Click arrow to add another value)
mechanism:
5-HT2A agonist (26) · GABAA positive allosteric modulator (21) · Monoamine releasing agent (9) · CB1/CB2 agonist (7) · Dopamine/norepinephrine reuptake inhibitor (5) · Potent 5-HT2A agonist (5) · LSD analogue; 5-HT2A agonist (4) · Mu-opioid receptor agonist (4) · Prodrug of LSD; 5-HT2A agonist (4) · Potent mu-opioid receptor agonist (3) · Serotonin/norepinephrine/dopamine releasing agent (3) · Cathinone analogue; monoamine reuptake inhibitor (2) · Dopamine and norepinephrine reuptake inhibitor (2) · NMDA antagonist (2) · Prodrug of GHB (2)
uses:
None (162) · Mild to moderate pain; cough suppression (low-dose). (1) · No approved medical problem. Encountered as a designer/research benzodiazepine and, increasingly, as an adulterant in illicit opioid supplies. (1) · '"`UNIQ--vote-00000069-QINU`"', '"`UNIQ--vote-0000006A-QINU`"', '"`UNIQ--vote-0000006B-QINU`"' (1)
starting dose:
None (162) · 0.25 mg (1) · Adult: 15–60 mg every 4 hours as needed. (1) · No medical dose. Active recreational doses reported in the 0.5–1.5 mg range (similar potency to alprazolam). (1)
preparations:
None (162) · 0.25 mg, 0.5 mg, 1 mg, 2 mg tablets (immediate-release and orally disintegrating); 0.5 mg, 1 mg, 2 mg, 3 mg extended-release tablets; 1 mg/mL oral concentrate (1) · Illicit tablets ("bars"), powders, blotter, occasionally solutions. No pharmaceutical product exists. (1) · Tablet (15, 30, 60 mg); oral solution; combination products (with [[Acetaminophen|acetaminophen]] or ibuprofen). (1)
fda max:
None (162) · 10 mg/d (1) · 360 mg/day (1) · N/A (never approved) (1)
routes:
None (162) · intranasal; rectal and IV reported. (1) · Oral (2) · PO (only formulation marketed in the US). (1) · sublingual (1)
onset:
None (162) · 30-60 min (immediate-release); 1-2 h (extended-release) (1) · 30–60 min (PO) (1) · ~20–40 min PO; faster sublingual/intranasal. (1)
duration:
None (162) · 4–6 hours (1) · 6 h (immediate-release); ~11 h (extended-release) (1) · 6–10 h subjective; full pharmacologic effect considerably longer. (1)
halflife:
None (162) · 11-13 h (immediate-release); 11-16 h (extended-release) (1) · 2.5–3 hours (1) · Estimated ~12–17 h (some sources cite up to ~21 h); active metabolites prolong effect. (1)
bioavailability:
None (162) · 80-90% oral (1) · Not formally characterized in humans. (1) · ~50% (variable, CYP2D6-dependent for analgesic effect). (1)
pregnancy:
None (162) · Avoid. Benzodiazepines are associated with neonatal sedation, floppy-infant syndrome, and withdrawal; teratogenic signal weak but non-zero. Designer benzo with no safety data, assume worst-case. (1) · Avoid; risk of neonatal opioid withdrawal with chronic use; UM-mother breastfeeding contraindicated. (1) · Category D'"`UNIQ--ref-0000006C-QINU`"' (1)
legal:
None (163) · Schedule IV (US) (1) · US Schedule II (single-entity); Schedule III–V (combination products by content). (1)

Showing below up to 173 results in range #1 to #173.

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