Jump to content

Drilldown: Medicines

Choose a table:


Medicines > classes : Analgesic or Beta Blocker or Opioid

Use the filters below to narrow your results.

generic:
7-Hydroxymitragynine (1) · Acetylfentanyl (1) · Alfentanil (1) · Bisoprolol (1) · Buprenorphine (1) · Butorphanol (1) · Carfentanil (1) · Codeine (2) · Desomorphine (1) · Dextropropoxyphene (1) · Diacetylmorphine (1) · Dihydrocodeine (1) · Esmolol (1) · Ethylmorphine (1) · Fentanyl (1) · Hydrocodone (1) · Hydromorphone (1) · Kratom (1) · Levorphanol (1) · Meperidine (1) · Methadone (1) · Metoprolol (1) · Mitragynine (1) · Nadolol (1) · Nalbuphine (1) · Nebivolol (1) · O-Desmethyltramadol (1) · Oxymorphone (1) · Papaverine (1) · Pentazocine (1) · Propranolol (1) · Remifentanil (1) · Sotalol (1) · Sufentanil (1) · Tapentadol (1) · Thebaine (1) · Tianeptine (1) · U-47700 (1)
brand:
None (12) · (multiple, generic dominant) (1) · Alfenta (1) · Betapace (1) · Brevibloc (1) · Bystolic (1) · Corgard (1) · Darvon (1) · Demerol (1) · Dilaudid (1) · Dolophine (1) · Duragesic (1) · Heroin (1) · Inderal (1) · Krokodil (1) · Lopressor (tartrate), Toprol XL (succinate) (1) · Nubain (1) · Nucynta (1) · O-DSMT (1) · Opana (1) · Stablon (1) · Stadol (1) · Suboxone (1) · Sufenta (1) · Talwin (1) · Ultiva (1) · Vicodin (1) · Zebeta (1)
classes: (Click arrow to add another value)
mechanism:
None (3) · Active metabolite of tramadol; mu-opioid agonist (1) · Cardioselective β1-adrenergic antagonist. Selectivity is dose-dependent and partially lost at higher doses. (1) · Extremely potent mu-opioid receptor agonist (1) · Highly potent mu-opioid receptor agonist (1) · Highly β1-selective adrenergic antagonist. Greater selectivity than metoprolol or atenolol. (1) · Kappa agonist; mu antagonist (1) · Kappa agonist; mu partial agonist (1) · Kappa agonist; mu partial agonist/antagonist (1) · Mitragynine/7-hydroxymitragynine; mu-opioid partial agonist (1) · Mu-opioid agonist; modulates glutamate AMPA receptors (1) · Mu-opioid agonist; norepinephrine reuptake inhibitor (1) · Mu-opioid receptor agonist (4) · Mu-opioid receptor agonist; fentanyl analogue (1) · Mu-opioid receptor agonist; NMDA antagonist (1) · Mu-opioid receptor agonist; prodrug (metabolized to morphine) (1) · Mu-opioid receptor agonist; sodium channel blocker (1) · Mu/kappa/delta agonist; NMDA antagonist (1) · Non-selective competitive antagonist at β1 and β2 adrenergic receptors. Lipophilic; significant blood–brain barrier penetration, accounting for its CNS effects. (1) · Opioid receptor partial agonist/antagonist; toxic alkaloid (1) · Partial mu-opioid agonist; kappa antagonist (1) · Partial mu-opioid receptor agonist; alpha-2 agonist (1) · Phosphodiesterase inhibitor; calcium channel blocker (1) · Potent mu-opioid receptor agonist (6) · Prodrug of morphine; mu-opioid receptor agonist (1) · Prodrug; converted to [[Morphine|morphine]] by [[Enzyme:CYP2D6|CYP2D6]] for analgesic action. (1) · Selective mu-opioid receptor agonist (1) · The d-enantiomer is a highly β1-selective antagonist; the l-enantiomer triggers endothelial nitric-oxide–mediated vasodilation. Unique among beta blockers for this NO mechanism. (1) · Ultra-short-acting mu-opioid agonist (1)
uses:
None (34) · Mild to moderate pain; cough suppression (low-dose). (1) · '"`UNIQ--vote-000004F5-QINU`"', '"`UNIQ--vote-000004F6-QINU`"', '"`UNIQ--vote-000004F7-QINU`"', '"`UNIQ--vote-000004F8-QINU`"', '"`UNIQ--vote-000004F9-QINU`"' (1) · '"`UNIQ--vote-0000059D-QINU`"' (1) · '"`UNIQ--vote-000005E7-QINU`"', '"`UNIQ--vote-000005E8-QINU`"', '"`UNIQ--vote-000005E9-QINU`"', '"`UNIQ--vote-000005EA-QINU`"', '"`UNIQ--vote-000005EB-QINU`"' (1) · '"`UNIQ--vote-00000636-QINU`"', '"`UNIQ--vote-00000637-QINU`"', '"`UNIQ--vote-00000638-QINU`"' (1)
starting dose:
None (34) · 10–40 mg (situational anxiety); 40 mg BID (HTN) (1) · 2.5–5 mg daily (HTN); 1.25 mg daily (HFrEF, slow titration) (1) · 25–50 mg BID (tartrate); 25–100 mg daily (succinate); 12.5 mg daily in HFrEF (1) · 5 mg daily (1) · Adult: 15–60 mg every 4 hours as needed. (1)
preparations:
None (34) · 10, 20, 40, 60, 80 mg tabs; 60/80/120/160 mg ER caps; 1 mg/mL IV (1) · 2.5, 5, 10, 20 mg tabs (1) · 5, 10 mg tabs (1) · Tablet (15, 30, 60 mg); oral solution; combination products (with [[Acetaminophen|acetaminophen]] or ibuprofen). (1) · Tartrate: 25, 50, 100 mg tabs; 1 mg/mL IV. Succinate ER: 25, 50, 100, 200 mg. (1)
fda max:
None (34) · 20 mg/d (1) · 360 mg/day (1) · 40 mg/d (1) · 400 mg/d (1) · 640 mg/d (HTN); 240 mg/d (migraine) (1)
routes:
None (34) · IV (2) · Oral (4) · PO (only formulation marketed in the US). (1)
onset:
None (34) · 1–2 h (2) · 1–2 h (PO), immediate (IV) (1) · 1–2 h (PO); immediate (IV) (1) · 30–60 min (PO) (1)
duration:
None (34) · 24 h (2) · 4–6 hours (1) · 6–12 h (IR); 24 h (ER) (1) · 6–12 h (tartrate); 24 h (succinate) (1)
halflife:
None (34) · 2.5–3 hours (1) · 3–6 h (1) · 3–7 h (1) · 9–12 h (1) · ~10 h (CYP2D6 extensive metabolizers); up to 31 h (poor metabolizers) (1)
bioavailability:
None (34) · ~12% (extensive metabolizers); ~96% (poor metabolizers) (1) · ~25% (extensive hepatic first-pass) (1) · ~50% (1) · ~50% (variable, CYP2D6-dependent for analgesic effect). (1) · ~90% (low first-pass) (1)
pregnancy:
None (34) · Avoid; risk of neonatal opioid withdrawal with chronic use; UM-mother breastfeeding contraindicated. (1) · Category C (4)
legal:
None (34) · Rx-only in US (4) · US Schedule II (single-entity); Schedule III–V (combination products by content). (1)

Showing below up to 57 results in range #1 to #57.

View (previous 250 | next 250) (20 | 50 | 100 | 250 | 500)


View (previous 250 | next 250) (20 | 50 | 100 | 250 | 500)

Retrieved from "https://pharmacopedia.wiki/p/Special:Drilldown/Medicines"