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Drilldown: Medicines

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Medicines > classes : Analgesic or Classic Psychedelic or TCA

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generic:
Codeine (2)
brand:
None (75) · (multiple, generic dominant) (1) · Anafranil (1) · Darvon (1) · Delysid (historical, Sandoz, withdrawn 1965) (1) · Demerol (1) · Dilaudid (1) · Dolophine (1) · Duragesic (1) · Ludiomil (1) · Norpramin (1) · Nubain (1) · Nucynta (1) · Opana (1) · Stadol (1) · Suboxone (1) · Surmontil (1) · Talwin (1) · Tofranil (1) · Vicodin (1) · Vivactil (1)
classes: (Click arrow to add another value)
mechanism:
5-HT2A agonist (26) · Potent 5-HT2A agonist (5) · LSD analogue; 5-HT2A agonist (4) · Mu-opioid receptor agonist (4) · Prodrug of LSD; 5-HT2A agonist (4) · Potent mu-opioid receptor agonist (3) · Serotonin and norepinephrine reuptake inhibitor (3) · Contains LSA (2) · Contains mescaline (2) · Selective norepinephrine reuptake inhibitor (2)
uses:
None (94) · Mild to moderate pain; cough suppression (low-dose). (1)
starting dose:
None (94) · Adult: 15–60 mg every 4 hours as needed. (1)
preparations:
None (94) · Tablet (15, 30, 60 mg); oral solution; combination products (with [[Acetaminophen|acetaminophen]] or ibuprofen). (1)
fda max:
None (94) · 360 mg/day (1)
routes:
None (93) · Oral (1) · PO (only formulation marketed in the US). (1)
onset:
None (93) · 30–60 min (PO) (1) · 30–60 minutes (1)
duration:
None (93) · 4–6 hours (1) · 8–12 hours (1)
halflife:
None (93) · 2.5–3 hours (1) · 3–5 hours (1)
bioavailability:
None (93) · 70–90% (oral) (1) · ~50% (variable, CYP2D6-dependent for analgesic effect). (1)
pregnancy:
None (93) · Avoid; risk of neonatal opioid withdrawal with chronic use; UM-mother breastfeeding contraindicated. (1) · Not established (1)
legal:
None (93) · Schedule I (United States) (1) · US Schedule II (single-entity); Schedule III–V (combination products by content). (1)

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