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Drilldown: Medicines

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Medicines > classes : Analgesic or Nootropic

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generic:
5-HTP (1) · Adrafinil (1) · Aniracetam (1) · Bromantane (1) · Buprenorphine (1) · Butorphanol (1) · Codeine (2) · Coluracetam (1) · Dextropropoxyphene (1) · Dihydrocodeine (1) · Ethylmorphine (1) · Fentanyl (1) · Hydrocodone (1) · Hydromorphone (1) · L-Theanine (1) · Levorphanol (1) · Meperidine (1) · Methadone (1) · Nalbuphine (1) · Noopept (1) · Oxiracetam (1) · Oxymorphone (1) · Papaverine (1) · Pentazocine (1) · Phenibut (1) · Phenylpiracetam (1) · Piracetam (1) · Pramiracetam (1) · Semax (1) · Tapentadol (1)
brand:
None (18) · (multiple, generic dominant) (1) · Darvon (1) · Demerol (1) · Dilaudid (1) · Dolophine (1) · Duragesic (1) · Nubain (1) · Nucynta (1) · Opana (1) · Stadol (1) · Suboxone (1) · Talwin (1) · Vicodin (1)
classes: (Click arrow to add another value)
mechanism:
ACTH analogue; BDNF upregulator (1) · AMPA modulator; catecholaminergic (1) · AMPA receptor modulator (1) · AMPA receptor positive allosteric modulator (2) · AMPA/NMDA modulator; NGF/BDNF upregulation (1) · Dopamine and serotonin reuptake inhibitor; actoprotector (1) · GABAB agonist; alpha-2-delta calcium channel ligand (1) · Glutamate receptor antagonist; GABA modulator (1) · High-affinity choline uptake enhancer (2) · Kappa agonist; mu antagonist (1) · Kappa agonist; mu partial agonist (1) · Kappa agonist; mu partial agonist/antagonist (1) · Mu-opioid agonist; norepinephrine reuptake inhibitor (1) · Mu-opioid receptor agonist (4) · Mu-opioid receptor agonist; NMDA antagonist (1) · Mu-opioid receptor agonist; prodrug (metabolized to morphine) (1) · Mu-opioid receptor agonist; sodium channel blocker (1) · Mu/kappa/delta agonist; NMDA antagonist (1) · Partial mu-opioid agonist; kappa antagonist (1) · Phosphodiesterase inhibitor; calcium channel blocker (1) · Potent mu-opioid receptor agonist (3) · Prodrug of modafinil (1) · Prodrug; converted to [[Morphine|morphine]] by [[Enzyme:CYP2D6|CYP2D6]] for analgesic action. (1) · Serotonin precursor; 5-hydroxytryptophan (1)
uses:
None (30) · Mild to moderate pain; cough suppression (low-dose). (1)
starting dose:
None (30) · Adult: 15–60 mg every 4 hours as needed. (1)
preparations:
None (30) · Tablet (15, 30, 60 mg); oral solution; combination products (with [[Acetaminophen|acetaminophen]] or ibuprofen). (1)
fda max:
None (30) · 360 mg/day (1)
routes:
None (30) · PO (only formulation marketed in the US). (1)
onset:
None (30) · 30–60 min (PO) (1)
duration:
None (30) · 4–6 hours (1)
halflife:
None (30) · 2.5–3 hours (1)
bioavailability:
None (30) · ~50% (variable, CYP2D6-dependent for analgesic effect). (1)
pregnancy:
None (30) · Avoid; risk of neonatal opioid withdrawal with chronic use; UM-mother breastfeeding contraindicated. (1)
legal:
None (30) · US Schedule II (single-entity); Schedule III–V (combination products by content). (1)

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