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Drilldown: Medicines

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Medicines > classes : Anticonvulsant or Daimonica or Opioid

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generic:
Codeine (2)
brand:
None (12)
classes: (Click arrow to add another value)
mechanism:
Potent mu-opioid receptor agonist (6) · Mu-opioid receptor agonist (4) · Sodium channel blocker (2)
uses:
None (50) · Mild to moderate pain; cough suppression (low-dose). (1) · '"`UNIQ--vote-00000006-QINU`"' (1) · '"`UNIQ--vote-00000008-QINU`"', '"`UNIQ--vote-00000009-QINU`"' (3)
starting dose:
None (54) · Adult: 15–60 mg every 4 hours as needed. (1)
preparations:
None (50) · Flowers or leaves infused or smoked. Highly variable potency; narrow toxic margin (1) · Leaves and seeds, traditionally smoked or infused. Possibly the original Pythia oracle plant (1) · Leaves, berries, root. Historically: belladonna cigarettes ("Asthmador") OTC in US until the 1970s (1) · Root, traditionally carved into ''mannikens'' or infused into wine (1) · Tablet (15, 30, 60 mg); oral solution; combination products (with [[Acetaminophen|acetaminophen]] or ibuprofen). (1)
fda max:
None (54) · 360 mg/day (1)
routes:
None (50) · inhalation (2) · Oral (4) · PO (only formulation marketed in the US). (1) · topical (1)
onset:
None (54) · 30–60 min (PO) (1)
duration:
None (54) · 4–6 hours (1)
halflife:
None (54) · 2.5–3 hours (1)
bioavailability:
None (54) · ~50% (variable, CYP2D6-dependent for analgesic effect). (1)
pregnancy:
None (54) · Avoid; risk of neonatal opioid withdrawal with chronic use; UM-mother breastfeeding contraindicated. (1)
legal:
None (53) · Plant unrestricted; pharmaceutical atropine Rx-only (1) · US Schedule II (single-entity); Schedule III–V (combination products by content). (1)

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