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Medicines > classes : Anticonvulsant or Opioid or [[:Category:Dibenzothiazepines|Dibenzothiazepine]]

Use the filters below to narrow your results.

generic:
Codeine (2)
brand:
None (12) · (multiple, generic dominant) (1) · Alfenta (1) · Aptiom (1) · Banzel (1) · Briviact (1) · Cerebyx (1) · Darvon (1) · Demerol (1) · Depakote (1) · Diacomit (1) · Dilantin (1) · Dilaudid (1) · Duragesic (1) · Epidiolex (1) · Felbatol (1) · Fintepla (1) · Fycompa (1) · Gabitril (1) · Heroin (1) · Krokodil (1) · Luminal (1) · Nubain (1) · Nucynta (1) · O-DSMT (1) · Onfi (1) · Opana (1) · Sabril (1) · Seroquel (1) · Stablon (1) · Stadol (1) · Sufenta (1) · Talwin (1) · Ultiva (1) · Vicodin (1) · Vimpat (1) · Xcopri (1) · Zarontin (1) · Zonegran (1)
classes: (Click arrow to add another value)
mechanism:
Potent mu-opioid receptor agonist (6) · Mu-opioid receptor agonist (4) · Sodium channel blocker (2)
uses:
None (48) · Mild to moderate pain; cough suppression (low-dose). (1) · '"`UNIQ--vote-0000008F-QINU`"', '"`UNIQ--vote-00000090-QINU`"', '"`UNIQ--vote-00000091-QINU`"', '"`UNIQ--vote-00000092-QINU`"' (1)
starting dose:
None (48) · 25 mg (schizophrenia, immediate-release); 50 mg (bipolar mania, immediate-release); 50 mg (Seroquel XR, schizophrenia or bipolar) (1) · Adult: 15–60 mg every 4 hours as needed. (1)
preparations:
None (48) · 25 mg, 50 mg, 100 mg, 200 mg, 300 mg, 400 mg immediate-release tablets; 50 mg, 150 mg, 200 mg, 300 mg, 400 mg extended-release tablets (Seroquel XR) (1) · Tablet (15, 30, 60 mg); oral solution; combination products (with [[Acetaminophen|acetaminophen]] or ibuprofen). (1)
fda max:
None (48) · 360 mg/day (1) · 800 mg/day (1)
routes:
None (48) · Oral (1) · PO (only formulation marketed in the US). (1)
onset:
None (48) · 30-60 min (sedation); days to weeks (neuroleptic effect) (1) · 30–60 min (PO) (1)
duration:
None (48) · 4–6 hours (1) · 6-8 h (immediate-release); 24 h (extended-release) (1)
halflife:
None (48) · 2.5–3 hours (1) · ~6 h (parent compound, immediate-release); ~9-12 h (active metabolite N-desalkylquetiapine, also called norquetiapine) (1)
bioavailability:
None (48) · Tablet ~100% relative to oral solution; extensive first-pass metabolism (1) · ~50% (variable, CYP2D6-dependent for analgesic effect). (1)
pregnancy:
None (48) · Avoid; risk of neonatal opioid withdrawal with chronic use; UM-mother breastfeeding contraindicated. (1) · Pregnancy categories were retired by FDA in 2015. Quetiapine has reassuring active-comparator cohort data without consistent teratogenic signal; among the preferred neuroleptics when treatment is clinically necessary in pregnancy. See pregnancy_details for the full citation set. (1)
legal:
None (48) · US Schedule II (single-entity); Schedule III–V (combination products by content). (1) · [[USLegal:Prescription only|Prescription only]]; not a controlled substance (1)

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