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Drilldown: Medicines

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Medicines > classes : Anticonvulsant or Opioid or [[:Category:Selective Serotonin Reuptake Inhibitors (SSRIs)|SSRI]]

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generic:
Codeine (2)
brand:
None (12)
classes: (Click arrow to add another value)
mechanism:
Potent mu-opioid receptor agonist (6) · Mu-opioid receptor agonist (4) · Sodium channel blocker (2)
uses:
None (50) · Mild to moderate pain; cough suppression (low-dose). (1) · '"`UNIQ--vote-00000042-QINU`"', '"`UNIQ--vote-00000043-QINU`"', '"`UNIQ--vote-00000044-QINU`"' (1)
starting dose:
None (50) · 10 mg (1) · Adult: 15–60 mg every 4 hours as needed. (1)
preparations:
None (50) · 10 mg, 20 mg, 40 mg caps (1) · Tablet (15, 30, 60 mg); oral solution; combination products (with [[Acetaminophen|acetaminophen]] or ibuprofen). (1)
fda max:
None (50) · 360 mg/day (1) · 40 mg/d (1)
routes:
None (50) · Oral (1) · PO (only formulation marketed in the US). (1)
onset:
None (51) · 30–60 min (PO) (1)
duration:
None (50) · 4–6 hours (1) · Very long (1)
halflife:
None (50) · 1–4 days (7–15 days for norfluoxetine) (1) · 2.5–3 hours (1)
bioavailability:
None (50) · 70–90% (oral) (1) · ~50% (variable, CYP2D6-dependent for analgesic effect). (1)
pregnancy:
None (50) · Avoid; risk of neonatal opioid withdrawal with chronic use; UM-mother breastfeeding contraindicated. (1) · Category C'"`UNIQ--ref-00000045-QINU`"' (1)
legal:
None (50) · US Schedule II (single-entity); Schedule III–V (combination products by content). (1) · [[USLegal:Prescription only|Rx-only]] in US (1)

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