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Drilldown: Medicines

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Medicines > classes : Botanical or Opioid or [[:Category:Bacteriostatic_antibiotics|Bacteriostatic antibiotic]]

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generic:
Codeine (2)
brand:
None (32) · (multiple, generic dominant) (1) · Alfenta (1) · Darvon (1) · Demerol (1) · Dilaudid (1) · Duragesic (1) · Heroin (1) · Krokodil (1) · Nubain (1) · Nucynta (1) · O-DSMT (1) · Opana (1) · Stablon (1) · Stadol (1) · Sufenta (1) · Talwin (1) · Ultiva (1) · Vibramycin, Doryx, Oracea, Adoxa, Monodox, Acticlate (1) · Vicodin (1)
classes: (Click arrow to add another value)
mechanism:
Potent mu-opioid receptor agonist (6) · Mu-opioid receptor agonist (4) · Contains LSA (2) · Contains mescaline (2)
uses:
None (49) · Mild to moderate pain; cough suppression (low-dose). (1) · '"`UNIQ--vote-00000475-QINU`"', '"`UNIQ--vote-00000476-QINU`"', '"`UNIQ--vote-00000477-QINU`"', '"`UNIQ--vote-00000478-QINU`"', '"`UNIQ--vote-00000479-QINU`"', '"`UNIQ--vote-0000047A-QINU`"', '"`UNIQ--vote-0000047B-QINU`"', '"`UNIQ--vote-0000047C-QINU`"' (1)
starting dose:
None (49) · 100 mg PO BID; rickettsial 200 mg/d; doxy-PEP 200 mg within 72 hours after condomless sex (1) · Adult: 15–60 mg every 4 hours as needed. (1)
preparations:
None (49) · 50 mg, 75 mg, 100 mg, 150 mg tablets and capsules; delayed-release; suspension; IV (1) · Tablet (15, 30, 60 mg); oral solution; combination products (with [[Acetaminophen|acetaminophen]] or ibuprofen). (1)
fda max:
None (49) · 360 mg/day (1) · ~200 mg/d for most indications; higher doses for severe infections (1)
routes:
None (49) · IV (1) · Oral (1) · PO (only formulation marketed in the US). (1)
onset:
None (49) · 30–60 min (PO) (1) · Hours (1)
duration:
None (49) · 12 hours (1) · 4–6 hours (1)
halflife:
None (49) · 16-22 hours'"`UNIQ--ref-0000047D-QINU`"' (1) · 2.5–3 hours (1)
bioavailability:
None (49) · ~50% (variable, CYP2D6-dependent for analgesic effect). (1) · ~95% (oral; reduced by dairy, antacids, iron via divalent-cation chelation, though less than for tetracycline itself)'"`UNIQ--ref-0000047E-QINU`"' (1)
pregnancy:
None (50) · Avoid; risk of neonatal opioid withdrawal with chronic use; UM-mother breastfeeding contraindicated. (1)
legal:
None (49) · US Schedule II (single-entity); Schedule III–V (combination products by content). (1) · [[USLegal:Prescription only|Rx-only]] in US (1)

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