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Drilldown: Medicines

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Medicines > classes : Classic Psychedelic or Non-selective or Opioid

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generic:
Codeine (2)
brand:
None (81) · (multiple, generic dominant) (1) · Alfenta (1) · Darvon (1) · Delysid (historical, Sandoz, withdrawn 1965) (1) · Demerol (1) · Dilaudid (1) · Dolophine (1) · Duragesic (1) · Heroin (1) · Inderal (1) · Krokodil (1) · Nubain (1) · Nucynta (1) · O-DSMT (1) · Opana (1) · Stablon (1) · Stadol (1) · Suboxone (1) · Sufenta (1) · Talwin (1) · Ultiva (1) · Vicodin (1)
classes: (Click arrow to add another value)
mechanism:
5-HT2A agonist (26) · Potent mu-opioid receptor agonist (6) · Potent 5-HT2A agonist (5) · LSD analogue; 5-HT2A agonist (4) · Mu-opioid receptor agonist (4) · Prodrug of LSD; 5-HT2A agonist (4) · Contains LSA (2) · Contains mescaline (2)
uses:
None (101) · Mild to moderate pain; cough suppression (low-dose). (1) · '"`UNIQ--vote-000005E7-QINU`"', '"`UNIQ--vote-000005E8-QINU`"', '"`UNIQ--vote-000005E9-QINU`"', '"`UNIQ--vote-000005EA-QINU`"', '"`UNIQ--vote-000005EB-QINU`"' (1)
starting dose:
None (101) · 10–40 mg (situational anxiety); 40 mg BID (HTN) (1) · Adult: 15–60 mg every 4 hours as needed. (1)
preparations:
None (101) · 10, 20, 40, 60, 80 mg tabs; 60/80/120/160 mg ER caps; 1 mg/mL IV (1) · Tablet (15, 30, 60 mg); oral solution; combination products (with [[Acetaminophen|acetaminophen]] or ibuprofen). (1)
fda max:
None (101) · 360 mg/day (1) · 640 mg/d (HTN); 240 mg/d (migraine) (1)
routes:
None (100) · IV (1) · Oral (2) · PO (only formulation marketed in the US). (1)
onset:
None (100) · 1–2 h (PO), immediate (IV) (1) · 30–60 min (PO) (1) · 30–60 minutes (1)
duration:
None (100) · 4–6 hours (1) · 6–12 h (IR); 24 h (ER) (1) · 8–12 hours (1)
halflife:
None (100) · 2.5–3 hours (1) · 3–5 hours (1) · 3–6 h (1)
bioavailability:
None (100) · 70–90% (oral) (1) · ~25% (extensive hepatic first-pass) (1) · ~50% (variable, CYP2D6-dependent for analgesic effect). (1)
pregnancy:
None (100) · Avoid; risk of neonatal opioid withdrawal with chronic use; UM-mother breastfeeding contraindicated. (1) · Category C (1) · Not established (1)
legal:
None (100) · Rx-only in US (1) · Schedule I (United States) (1) · US Schedule II (single-entity); Schedule III–V (combination products by content). (1)

Showing below up to 103 results in range #1 to #103.

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