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Medicines > classes : Neuroleptic or Opioid or Xanthine

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generic:
Codeine (2)
brand:
None (15) · ''Coffea arabica'', ''Coffea canephora'' (robusta) (1) · (multiple, generic dominant) (1) · Alfenta (1) · Clozaril (1) · Darvon (1) · Demerol (1) · Dilaudid (1) · Dolophine (1) · Duragesic (1) · Fanapt (1) · Geodon (1) · Heroin (1) · Inapsine (1) · Invega (1) · Krokodil (1) · Latuda (1) · Loxitane (1) · Mellaril (1) · Moban (1) · Navane (1) · Nubain (1) · Nucynta (1) · O-DSMT (1) · Opana (1) · Orap (1) · Prolixin (1) · Saphris (1) · Stablon (1) · Stadol (1) · Stelazine (1) · Suboxone (1) · Sufenta (1) · Talwin (1) · Thorazine (1) · Trilafon (1) · Ultiva (1) · Vicodin (1)
classes: (Click arrow to add another value)
mechanism:
Potent mu-opioid receptor agonist (6) · Mu-opioid receptor agonist (4) · Phenothiazine D2 antagonist (4)
uses:
None (50) · Mild to moderate pain; cough suppression (low-dose). (1) · '"`UNIQ--vote-000000CF-QINU`"', '"`UNIQ--vote-000000D0-QINU`"', '"`UNIQ--vote-000000D1-QINU`"' (1)
starting dose:
None (50) · Adult: 15–60 mg every 4 hours as needed. (1) · One cup (~80–145 mg caffeine for brewed; 60–100 mg for instant) (1)
preparations:
None (50) · Roasted beans, ground; brewed (drip, French press, espresso, cold brew, percolated) (1) · Tablet (15, 30, 60 mg); oral solution; combination products (with [[Acetaminophen|acetaminophen]] or ibuprofen). (1)
fda max:
None (51) · 360 mg/day (1)
routes:
None (50) · Oral (1) · PO (only formulation marketed in the US). (1)
onset:
None (50) · 30–60 min (PO) (1) · ~15–30 min (1)
duration:
None (50) · 3–5 h (subjective) (1) · 4–6 hours (1)
halflife:
None (50) · 2.5–3 hours (1) · ~5 h (caffeine) (1)
bioavailability:
None (50) · ~50% (variable, CYP2D6-dependent for analgesic effect). (1) · ~99% (caffeine) (1)
pregnancy:
None (50) · Avoid; risk of neonatal opioid withdrawal with chronic use; UM-mother breastfeeding contraindicated. (1) · Limit to <200 mg/d (~2 cups brewed) (1)
legal:
None (50) · Unrestricted (food) (1) · US Schedule II (single-entity); Schedule III–V (combination products by content). (1)

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