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Drilldown: Medicines

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Medicines > classes: Anxiolytic & duration : Long or None

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generic:
Bromazepam (1) · Chlordiazepoxide (1) · Clorazepate (1) · Etizolam (1) · Kava (1) · Meprobamate (1) · Metizolam (1) · Oxazepam (1) · Pyrazolam (1) · Sertraline (1)
brand:
None (4) · Lexotan (1) · Librium (1) · Miltown (1) · Serax (1) · Tranxene (1) · Zoloft (1)
classes: (Click arrow to add another value)
mechanism:
GABAA modulator; glycine receptor agonist (1) · GABAA positive allosteric modulator (5) · GABAA positive allosteric modulator; low sedation (1) · GABAA positive allosteric modulator; prodrug of desmethyldiazepam (1) · Kavalactones; GABAA modulator; sigma receptor activity (1) · TrkB/BDNF'"`UNIQ--ref-00000084-QINU`"' '"`UNIQ--vote-00000085-QINU`"' (1)
uses:
None (10)
starting dose:
None (9) · 25 mg (1)
preparations:
None (9) · 25 mg, 50 mg, 100 mg tablets; oral concentrate 20 mg/mL (1)
fda max:
None (9) · 200 mg/d (1)
routes:
None (9) · Oral (1)
onset:
None (9) · Anxiolysis classically 3-4 weeks, continuing improvement to 8-12 weeks (1)
duration: (Click arrow to add another value)
halflife:
None (9) · ~26 h (sertraline; range 13-45 h, longer in females); ~62-104 h (N-desmethylsertraline, weakly active) (1)
bioavailability:
None (9) · Absolute bioavailability not precisely characterized; food modestly increases exposure (1)
pregnancy:
None (9) · Category C'"`UNIQ--ref-0000008F-QINU`"' (1)
legal:
None (9) · Rx-only in US (1)

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