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Drilldown: Medicines

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Medicines > classes: Anxiolytic & halflife : 11-13 h (immediate-release); 11-16 h (extended-release) or ~12 hours

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generic:
Alprazolam (1) · Duloxetine (1)
brand:
Cymbalta, Drizalma Sprinkle, Irenka, Yentreve (1) · Xanax (1)
classes: (Click arrow to add another value)
mechanism:
GABA-A positive allosteric modulator'"`UNIQ--ref-00000067-QINU`"' '"`UNIQ--vote-00000068-QINU`"' (1) · Serotonin–norepinephrine reuptake inhibition (balanced) (1)
uses:
Depression, anxiety, neuropathic pain, fibromyalgia, chronic musculoskeletal pain (1) · '"`UNIQ--vote-00000069-QINU`"', '"`UNIQ--vote-0000006A-QINU`"', '"`UNIQ--vote-0000006B-QINU`"' (1)
starting dose:
None (1) · 0.25 mg (1)
preparations:
None (1) · 0.25 mg, 0.5 mg, 1 mg, 2 mg tablets (immediate-release and orally disintegrating); 0.5 mg, 1 mg, 2 mg, 3 mg extended-release tablets; 1 mg/mL oral concentrate (1)
fda max:
None (1) · 10 mg/d (1)
routes:
Oral (2)
onset:
30-60 min (immediate-release); 1-2 h (extended-release) (1) · Mood: 2–4 weeks. Pain: often within 1–2 weeks. (1)
duration:
6 h (immediate-release); ~11 h (extended-release) (1) · Chronic daily dosing (1)
halflife: (Click arrow to add another value)
bioavailability:
80-90% oral (1) · ~50% (highly variable) (1)
pregnancy:
Category C (1) · Category D'"`UNIQ--ref-0000006C-QINU`"' (1)
legal:
Rx-only (1) · Schedule IV (US) (1)

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