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Medicines > fda max : 15 mg/day (oral); 30 mg IV once daily (Anjeso) or 600 mg/d & routes: intravenous

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generic:
Meloxicam (1)
brand:
Mobic, Vivlodex (lower-dose capsules), Anjeso (IV) (1)
classes:
preferential COX-2)]] (1) · [[:Category:Analgesics|Analgesic]] (1) · [[:Category:NSAIDs|Non-steroidal anti-inflammatory (NSAID (1)
mechanism:
'"`UNIQ--vote-00000019-QINU`"' Once-daily dosing is a clinical advantage over short-half-life NSAIDs'"`UNIQ--ref-0000001A-QINU`"'. (1)
uses:
'"`UNIQ--vote-0000001B-QINU`"', '"`UNIQ--vote-0000001C-QINU`"', '"`UNIQ--vote-0000001D-QINU`"', '"`UNIQ--vote-0000001E-QINU`"', '"`UNIQ--vote-0000001F-QINU`"' (1)
starting dose:
7.5 mg PO once daily; titrate to 15 mg daily if needed. Vivlodex 5 mg PO once daily, max 10 mg (1)
preparations:
Tablets 7.5, 15 mg (Mobic); capsules 5, 10 mg (Vivlodex); oral suspension 7.5 mg/5 mL; injection 30 mg/mL (Anjeso) (1)
fda max: (Click arrow to add another value)
routes: (Click arrow to add another value)
onset:
Analgesic effect within hours; full anti-inflammatory effect over 1-2 weeks (1)
duration:
24 hours (once-daily dosing supported by long half-life) (1)
halflife:
15-20 hours'"`UNIQ--ref-00000020-QINU`"' (1)
bioavailability:
~89% (oral)'"`UNIQ--ref-00000021-QINU`"' (1)
pregnancy:
Avoid from 20 weeks gestation onward per FDA's 2020 expanded NSAID warning (fetal renal dysfunction, oligohydramnios); contraindicated from 30 weeks (risk of premature ductus arteriosus closure)'"`UNIQ--ref-00000022-QINU`"' (1)
legal:
[[USLegal:Prescription only|Rx-only]] in US (1)

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