Drilldown: Medicines
Use the filters below to narrow your results.
generic:
brand:
classes:
Research material (131) ·
Classic Psychedelic (69) ·
Stimulant (43) ·
Opioid (29) ·
Sedative-Hypnotic (29) ·
Tryptamine (26) ·
Phenethylamine (25) ·
Botanical (23) ·
Benzodiazepine (22) ·
Anticonvulsant (19) ·
Dissociative (19) ·
Antidepressant (17) ·
Antiparkinsonian (16) ·
Antipsychotic (16) ·
Empathogen (16) ·
Analgesic (15) ·
Neuroleptic (15) ·
Cathinone (14) ·
Plant Medicine (14) ·
Nootropic (13)
mechanism:
5-HT2A agonist (27) ·
GABAA positive allosteric modulator (22) ·
None (20) ·
Monoamine releasing agent (11) ·
CB1/CB2 agonist (7) ·
Potent mu-opioid receptor agonist (6) ·
Sodium channel blocker (6) ·
Dopamine/norepinephrine reuptake inhibitor (5) ·
GABAA potentiator; NMDA antagonist (5) ·
Phenothiazine D2 antagonist (5) ·
Potent 5-HT2A agonist (5) ·
5-HT1B/1D agonist (4) ·
LSD analogue; 5-HT2A agonist (4) ·
Mu-opioid receptor agonist (4) ·
Muscarinic receptor antagonist (4) ·
Prodrug of LSD; 5-HT2A agonist (4) ·
Selective norepinephrine reuptake inhibitor (4)
uses:
None (394) ·
Pain, cough, disquiet (1) ·
'"`UNIQ--vote-00000006-QINU`"' (4) ·
'"`UNIQ--vote-00000008-QINU`"', '"`UNIQ--vote-00000009-QINU`"' (5) ·
'"`UNIQ--vote-0000004B-QINU`"', '"`UNIQ--vote-0000004C-QINU`"', '"`UNIQ--vote-0000004D-QINU`"', '"`UNIQ--vote-0000004E-QINU`"' (1) ·
'"`UNIQ--vote-0000004C-QINU`"', '"`UNIQ--vote-0000004D-QINU`"', '"`UNIQ--vote-0000004E-QINU`"' (1) ·
'"`UNIQ--vote-00000065-QINU`"' (1) ·
'"`UNIQ--vote-000000AD-QINU`"', '"`UNIQ--vote-000000AE-QINU`"' (1) ·
'"`UNIQ--vote-0000013A-QINU`"', '"`UNIQ--vote-0000013B-QINU`"', '"`UNIQ--vote-0000013C-QINU`"', '"`UNIQ--vote-0000013D-QINU`"' (1) ·
'"`UNIQ--vote-000001F8-QINU`"', '"`UNIQ--vote-000001F9-QINU`"', '"`UNIQ--vote-000001FA-QINU`"' (1) ·
'"`UNIQ--vote-00000374-QINU`"', '"`UNIQ--vote-00000375-QINU`"', '"`UNIQ--vote-00000376-QINU`"', '"`UNIQ--vote-00000377-QINU`"' (1) ·
'"`UNIQ--vote-000003A0-QINU`"', '"`UNIQ--vote-000003A1-QINU`"' (1) ·
'"`UNIQ--vote-00000475-QINU`"', '"`UNIQ--vote-00000476-QINU`"', '"`UNIQ--vote-00000477-QINU`"', '"`UNIQ--vote-00000478-QINU`"', '"`UNIQ--vote-00000479-QINU`"', '"`UNIQ--vote-0000047A-QINU`"', '"`UNIQ--vote-0000047B-QINU`"', '"`UNIQ--vote-0000047C-QINU`"' (1) ·
'"`UNIQ--vote-0000069B-QINU`"', '"`UNIQ--vote-0000069C-QINU`"' (1) ·
'"`UNIQ--vote-00000722-QINU`"', '"`UNIQ--vote-00000723-QINU`"', '"`UNIQ--vote-00000724-QINU`"', '"`UNIQ--vote-00000725-QINU`"' (1) ·
'"`UNIQ--vote-00000747-QINU`"', '"`UNIQ--vote-00000748-QINU`"' (1) ·
'"`UNIQ--vote-0000081E-QINU`"' (1) ·
'"`UNIQ--vote-00000A42-QINU`"', '"`UNIQ--vote-00000A43-QINU`"', '"`UNIQ--vote-00000A44-QINU`"', '"`UNIQ--vote-00000A45-QINU`"', '"`UNIQ--vote-00000A46-QINU`"' (1) ·
'"`UNIQ--vote-00000BA0-QINU`"', '"`UNIQ--vote-00000BA1-QINU`"', '"`UNIQ--vote-00000BA2-QINU`"' (1) ·
'"`UNIQ--vote-00000ECF-QINU`"', '"`UNIQ--vote-00000ED0-QINU`"', '"`UNIQ--vote-00000ED1-QINU`"', '"`UNIQ--vote-00000ED2-QINU`"' (1) ·
'"`UNIQ--vote-00001016-QINU`"', '"`UNIQ--vote-00001017-QINU`"', '"`UNIQ--vote-00001018-QINU`"', '"`UNIQ--vote-00001019-QINU`"' (1)
starting dose:
None (408) ·
0.5–1 oz (10–30 g) ground for psychoactive effect; far smaller for culinary use (1) ·
10-40 mg PO daily depending on hyperthyroidism severity; titrate by clinical and biochemical response (target TSH/free T4) (1) ·
100 mg PO BID; rickettsial 200 mg/d; doxy-PEP 200 mg within 72 hours after condomless sex (1) ·
12.5 mg PO once or twice daily. Titrate gradually: 25-50 mg/day increments every 1-2 days as tolerated. Target dose 300-450 mg/day in divided doses (BID or TID). Most patients stabilize between 200-600 mg/day. Therapeutic plasma level guide: target trough clozapine ≥350 ng/mL. (1) ·
12.5-25 mg PO once daily (1) ·
4-8 mg PO or IV every 8 hours as needed; 16 mg single dose preoperatively for PONV prevention (1) ·
40 mg SC every other week (most adult indications); IBD induction 160 mg week 0, 80 mg week 2, then 40 mg every other week (1) ·
Antenatal: Celestone Soluspan 12 mg IM q24h × 2 doses; topical: pea-sized amount BID; intra-articular varies by joint (1) ·
HRT cyclic: 200 mg PO HS days 1-12 of each month; continuous: 100 mg PO daily; ART luteal support 100 mg vaginal TID or 90 mg gel daily (1) ·
NVAF: 5 mg PO BID (2.5 mg BID if 2 of 3: age ≥80, weight ≤60 kg, serum creatinine ≥1.5 mg/dL); acute VTE: 10 mg BID for 7 days, then 5 mg BID (1) ·
One cup (~40–60 mg caffeine; about half of brewed coffee) (1) ·
Topical: pea-sized amount to dry face at bedtime, building from 2-3×/week to nightly as tolerated; oral APL: 45 mg/m²/d in divided doses (1) ·
Vulvovaginal: 150 mg PO single dose; oropharyngeal: 200 mg PO day 1, then 100 mg daily ×14 days; invasive candidiasis: 800 mg load, then 400 mg PO/IV daily; cryptococcal meningitis: 400-800 mg/d (1)
preparations:
None (392) ·
0.6 mg/5 mL oral solution; Celestone Soluspan 6 mg/mL IM/IA (mix of sodium phosphate + acetate); 0.05% and 0.1% topical cream/ointment/lotion/foam (various salts); augmented betamethasone 0.05% (super-high potency) (1) ·
12.5 mg capsules; 12.5, 25, 50 mg tablets (1) ·
2.5 mg, 5 mg tablets (1) ·
4 mg, 8 mg, 24 mg tablets; 4 mg, 8 mg orally disintegrating tablets; 4 mg/5 mL oral solution; IV (2 mg/mL) (1) ·
40 mg/0.4 mL or 40 mg/0.8 mL prefilled syringe and autoinjector pen; 10, 20, 80 mg pediatric/induction strengths (1) ·
5, 10 mg tablets (1) ·
50 mg, 75 mg, 100 mg, 150 mg tablets and capsules; delayed-release; suspension; IV (1) ·
50, 100, 150, 200 mg tablets; 10, 40 mg/mL oral suspension; 2 mg/mL IV (1) ·
A ''betel quid'': areca nut slice + betel leaf + slaked lime (calcium hydroxide) ± tobacco ± spices, chewed (1) ·
Acid/base extraction of fresh young grass for tryptamines; combined with an MAOI (1) ·
Bark/woody stem decocted with a DMT-source plant (''Psychotria viridis'', ''Diplopterys cabrerana'') to make ayahuasca (1) ·
Bright red seeds, traditionally ingested or smoked. Highly toxic, narrow margin between active and lethal (1) ·
Clozaril 25 mg and 100 mg tablets; FazaClo orally disintegrating tablets (12.5/25/100/150/200 mg); Versacloz oral suspension 50 mg/mL. All brands subject to identical REMS ANC monitoring requirements. Generic tablets widely available. (1) ·
Dried leaves and twigs, infused in a gourd (''mate'') and drunk through a metal straw (''bombilla'') (1) ·
Dried leaves, infused. Six major processings: white, green, yellow, oolong, black, pu-erh (1) ·
Fermented and roasted seeds, ground. Mexican tradition: drunk with chili, cornmeal, achiote. European tradition: with sugar and milk (1) ·
Flowers or leaves infused or smoked. Highly variable potency; narrow toxic margin (1) ·
Fresh nuts chewed; also dried and powdered (1) ·
Ground dried seed (nutmeg) or fruit aril (mace); occasionally infused (1) ·
Leaves and seeds, traditionally smoked or infused. Possibly the original Pythia oracle plant (1) ·
Oral 100, 200 mg capsules (peanut oil; check allergy); 100 mg vaginal insert (Endometrin); 4%, 8% vaginal gel (Crinone); IM 50 mg/mL (1) ·
Oral tablets 50 mg (ReVia, Depade, generics); Vivitrol extended-release IM suspension 380 mg single-dose vial; Contrave (naltrexone 8 mg + bupropion 90 mg ER tablets); compounded 1, 2, 3, 4.5 mg tablets/capsules for LDN (1) ·
Roasted seeds ground to powder, mixed with water; commercial syrups and energy drinks (1) ·
Root bark acid/base-extracted for DMT; or as the resurrected ''jurema preta'' brew (decocted with an MAOI such as ''Peganum harmala'') (1) ·
Root, traditionally carved into ''mannikens'' or infused into wine (1) ·
Tablets 5, 10, 40 mg (40 mg dispersible restricted to OTPs); oral concentrate 10 mg/mL; oral solution 1, 2, 10 mg/mL; injection 10 mg/mL (1) ·
Tablets: 100 mg, 200 mg (scored). [[Armodafinil]] (Nuvigil), the R-enantiomer of modafinil, is available separately as 50 mg, 150 mg, 200 mg, and 250 mg tablets. (1) ·
Toasted leaves and twigs decocted to a near-black concentrate (1) ·
Topical 0.01-0.1% creams, gels, micropsheres, lotions; oral 10 mg capsules (Vesanoid) (1)
fda max:
None (406) ·
10 mg BID for the first 7 days of acute VTE; otherwise 5 mg BID (1) ·
40 mg every week (selected indications); otherwise 40 mg every other week (1) ·
400 mg/day.'"`UNIQ--ref-0000006C-QINU`"' (1) ·
50 mg/d (hypertension); up to 200 mg/d (edema) (1) ·
50 mg/day oral; 380 mg/4 weeks IM (Vivitrol); 32 mg + 360 mg naltrexone/bupropion daily (Contrave maximum after titration) (1) ·
60 mg/d typical (1) ·
800 mg/d (severe invasive disease) (1) ·
900 mg/day (split into BID or TID dosing). Clinical practice rarely exceeds 600 mg/day; seizure risk increases substantially above 600 mg/day and requires consideration of prophylactic anticonvulsant.'"`UNIQ--ref-0000004A-QINU`"' (1) ·
Indication-dependent; 200-400 mg/d oral typical (1) ·
Indication-specific (1) ·
MOUD: typical effective max 24 mg/day sublingual (doses above offer limited additional mu-occupancy due to ceiling). Pain (Belbuca): 900 mcg every 12 hours. (1) ·
No formal hard ceiling; in MOUD maintenance, doses typically remain at or below 120 mg/day with higher doses reserved for documented under-treatment after careful clinical assessment (1) ·
Single doses ≤16 mg (FDA 2012 advisory withdrew the 32 mg single IV dose for QT-prolongation risk); 24-32 mg/d divided (1) ·
Topical: nightly; oral APL: 45 mg/m²/d (1) ·
~200 mg/d for most indications; higher doses for severe infections (1)
routes:
None (391) ·
buccal (Belbuca for pain) (1) ·
IA (1) ·
IM (3) ·
inhalation (2) ·
intramuscular (1) ·
intramuscular (depot) (1) ·
IV (4) ·
IV/IM (Buprenex). Oral swallowed: very low bioavailability due to first-pass; not therapeutic. (1) ·
Oral (22) ·
oral (APL only) (1) ·
Oral (buccal) (1) ·
Oral (primary) (1) ·
Oral (with MAOI) (2) ·
Oral only. No parenteral formulation (a major limitation in acute agitation requiring rapid tranquilization). (1) ·
SC (1) ·
SC depot (Sublocade) (1) ·
smoked (extracted DMT) (1) ·
Subcutaneous (1) ·
Sublingual (primary for MOUD) (1) ·
sublingual; rectal off-label (1) ·
Topical (2) ·
transdermal (Butrans) (1) ·
vaginal (1)
onset:
None (404) ·
15–30 min (1) ·
30 minutes PO; minutes IV (1) ·
Biochemical improvement within 2-4 weeks; full euthyroid state 6-12 weeks (1) ·
Clinical improvement within 24-72 hours (1) ·
Diuresis at 2 hours; antihypertensive effect within days, max at 3-4 weeks (1) ·
Hours (2) ·
Oral analgesic effect 30-60 minutes; opioid-withdrawal suppression 30 minutes (oral); IV ~10 minutes (1) ·
Oral peak plasma 1 hour; therapeutic opioid blockade within hours of first dose. IM Vivitrol: peak plasma 2-3 days; therapeutic blockade through the dosing interval. (1) ·
Oral peak plasma 2.5 hours. Clinical antipsychotic response typically emerges over weeks with continued titration; full response assessment requires 3-6 months at adequate therapeutic levels. (1) ·
Peak anticoagulant effect 3-4 hours (1) ·
Peak plasma concentration in 2-4 hours after oral administration. Clinically perceptible wakefulness-promoting effects typically begin within 1-2 hours of dosing.<sup class="pcp-cn" title="This claim needs a citation.">[[[Pharmacopedia:Citation needed|citation needed]]]</sup> (1) ·
Sedation/dizziness within hours of oral dose; endometrial effects over days (1) ·
Slow, 2–6 h (1) ·
Sublingual analgesic effect 30-60 minutes; MOUD craving suppression within hours; Butrans patch steady-state in 3 days. (1) ·
Symptomatic effect within weeks; full response by 12-24 weeks (1) ·
Topical: irritation within days; acne improvement 6-12 weeks; oral APL response within days (1)
duration:
None (404) ·
12 hours (2) ·
12–24 h or longer (1) ·
2 weeks per dose (1) ·
24 hours (2) ·
3–4 h (1) ·
4-12 hours (1) ·
6-12 hours (1) ·
Analgesic effect 4-8 hours (much shorter than half-life would suggest, due to receptor kinetics); MOUD effect (opioid withdrawal suppression) 24-36 hours per single daily dose (1) ·
Biologic 36-54 hours (long-acting) (1) ·
Due to the half-life of 12 hours (wide range), dosing is BID or TID. Once-daily dosing produces higher peak/trough fluctuations and is generally not used except for a single end-of-day dose in stable patients. (1) ·
Effective duration approximately 12-15 hours at the 200 mg dose, consistent with the elimination half-life. A single morning dose generally sustains wakefulness throughout the day without substantially disrupting nighttime sleep onset when taken early.'"`UNIQ--ref-0000006D-QINU`"' (1) ·
MOUD: 24-72 hours per sublingual dose (long; permits every-other-day or three-times-weekly dosing in stable patients); Butrans patch: 7 days; Sublocade depot: 28+ days; Buprenex IV/IM: 6-8 hours. (1) ·
N/A (1) ·
Oral mu-blockade clinically meaningful for 24-72 hours; IM Vivitrol blockade through 4 weeks. (1) ·
Oral: 8-12 hours; vaginal: 24+ hours; IM: days (1)
halflife:
None (408) ·
16-22 hours'"`UNIQ--ref-0000047D-QINU`"' (1) ·
3-6 hours (longer in hepatic impairment)'"`UNIQ--ref-00000378-QINU`"' (1) ·
6-15 hours'"`UNIQ--ref-0000013E-QINU`"' (1) ·
Buprenorphine sublingual: 24-42 hours (long, contributes to extended dosing intervals). Norbuprenorphine (active metabolite, weaker mu-agonist): 24-48 hours.'"`UNIQ--ref-0000004F-QINU`"' (1) ·
Naltrexone parent ~4 hours (oral); 6-beta-naltrexol (active metabolite) ~13 hours. Vivitrol depot terminal half-life 5-10 days with sustained release from microspheres maintaining blockade for the 4-week dosing interval.'"`UNIQ--ref-0000004F-QINU`"' (1) ·
Plasma ~5 hours; biologic ~36-54 hours'"`UNIQ--ref-0000101A-QINU`"' (1) ·
~0.5-2 hours (oral)'"`UNIQ--ref-00000BA3-QINU`"' (1) ·
~12 hours'"`UNIQ--ref-000001FB-QINU`"' (1) ·
~14 days'"`UNIQ--ref-00001103-QINU`"' (1) ·
~30 hours (long, supports once-daily dosing and substantial drug-interaction window after discontinuation)'"`UNIQ--ref-00000A47-QINU`"' (1) ·
~4-6 hours (plasma); intrathyroidal accumulation gives a much longer functional duration'"`UNIQ--ref-00000ED3-QINU`"' (1) ·
~5 h (caffeine) (1) ·
~5-20 hours (oral micronized; highly variable)'"`UNIQ--ref-00000726-QINU`"' (1)
bioavailability:
None (406) ·
65-75% (oral)'"`UNIQ--ref-0000013F-QINU`"' (1) ·
>90% (oral; not affected by food or gastric pH — a major practical advantage over itraconazole)'"`UNIQ--ref-00000A48-QINU`"' (1) ·
Approximately 50-60% (oral; subject to first-pass metabolism); food does not significantly affect absorption.'"`UNIQ--ref-0000004C-QINU`"' (1) ·
Oral bioavailability is not precisely established in the label but absorption is rapid and essentially complete. Food delays peak plasma concentration by approximately one hour but does not reduce the extent of absorption.'"`UNIQ--ref-0000006F-QINU`"' (1) ·
Oral ~70%; depot IM provides sustained release over weeks'"`UNIQ--ref-0000101B-QINU`"' (1) ·
Oral: very low (extensive first-pass); micronization improves uptake somewhat. Vaginal: high local effect with lower systemic levels (first-uterine-pass concentration)'"`UNIQ--ref-00000727-QINU`"' (1) ·
Topical: minimal systemic absorption with normal skin; oral: variable, induced metabolism with repeated dosing'"`UNIQ--ref-00000BA4-QINU`"' (1) ·
~30% (sublingual; the primary therapeutic route); ~10-20% (oral swallowed, low due to first-pass); ~50% (buccal Belbuca); transdermal Butrans bypasses first-pass.'"`UNIQ--ref-00000050-QINU`"' (1) ·
~5-40% (oral, highly variable due to extensive first-pass metabolism; mean ~5-10% for parent naltrexone with the majority of pharmacologic effect coming from 6-beta-naltrexol). IM Vivitrol bypasses first-pass entirely.'"`UNIQ--ref-00000050-QINU`"' (1) ·
~50% (oral; not significantly affected by food)'"`UNIQ--ref-000001FC-QINU`"' (1) ·
~60% (oral)'"`UNIQ--ref-00000379-QINU`"' (1) ·
~64% from SC depot'"`UNIQ--ref-00001104-QINU`"' (1) ·
~70-85% (oral, high relative to other opioids) (1) ·
~93% (oral)'"`UNIQ--ref-00000ED4-QINU`"' (1) ·
~95% (oral; reduced by dairy, antacids, iron via divalent-cation chelation, though less than for tetracycline itself)'"`UNIQ--ref-0000047E-QINU`"' (1)
pregnancy: (Click arrow to add another value)
legal: (Click arrow to add another value)
Showing below up to 250 results in range #1 to #250.
1
2
- 2-AI
- 2-FA
- 2-FDCK
- 2-FMA
- 25B-NBOH
- 25B-NBOMe
- 25C-NBOH
- 25C-NBOMe
- 25I-NBOH
- 25I-NBOMe
- 25N-NBOMe
- 2C-B-FLY
- 2C-C
- 2C-D
- 2C-E
- 2C-I
- 2C-P
- 2C-T-2
- 2C-T-7
3
4
- 4-AcO-DET
- 4-AcO-DiPT
- 4-AcO-DMT
- 4-AcO-MET
- 4-AcO-MiPT
- 4-FA
- 4-FMA
- 4-HO-DET
- 4-HO-DiPT
- 4-HO-DPT
- 4-HO-EPT
- 4-HO-MET
- 4-HO-MiPT
- 4-MeO-PCP
- 4F-EPH
- 4F-MPH
5
6
7
A
B
- Baeocystin
- Banisteriopsis caapi
- Benzocaine
- Benztropine
- Benzydamine
- Betamethasone
- Betel
- Biperiden
- Black Drink
- Blue lotus
- Brivaracetam
- Bromantane
- Bromazepam
- Bromo-DragonFLY
- Bromocriptine
- Brompheniramine
- Brugmansia
- Bufotenin
- Bupivacaine
- Buprenorphine
- Butalbital
- Butorphanol
- Butylone
C
- Cabergoline
- Caffeine
- Calea zacatechichi
- Cannabidiol
- Carbidopa/levodopa
- Carfentanil
- Carisoprodol
- Cathinone
- CBG
- CBN
- Cenobamate
- Chlordiazepoxide
- Chloroform
- Chlorpheniramine
- Chlorpromazine
- Chlorzoxazone
- Chocolate
- Clobazam
- Clomipramine
- Clonazolam
- Clorazepate
- Clozapine
- Cocaine
- Codeine
- Coluracetam
- Curare
- Cyclazodone
D
- Datura
- Delta-10-THC
- Delta-8-THC
- Deschloroetizolam
- Deschloroketamine
- Desflurane
- Desipramine
- Desomorphine
- Desoxypipradrol
- DET
- Dexmedetomidine
- Dextroamphetamine
- Dextromethorphan
- Dextropropoxyphene
- Dextrorphan
- Diacetylmorphine
- Diclazepam
- Diethyl ether
- Dihydrocodeine
- Dihydroergotamine
- Dimenhydrinate
- Diphenidine
- DiPT
- Disulfiram
- DOB
- DOC
- DOI
E
- Eletriptan
- Entacapone
- Ephedrine
- Ephenidine
- Ephylone
- EPT
- Ergotamine
- Escaline
- Eslicarbazepine
- Esmolol
- Estazolam
- Eszopiclone
- ETH-LAD
- Ethcathinone
- Ethchlorvynol
- Ethosuximide
- Ethylmorphine
- Ethylone
- Ethylphenidate
- Eticyclidine
- Etizolam
- Etomidate
F
- F-Phenibut
- Felbamate
- Fenethylline
- Fenfluramine
- Fentanyl
- Flualprazolam
- Flubromazepam
- Flubromazolam
- Fluconazole
- Flunitrazepam
- Flunitrazolam
- Fluphenazine
- Flurazepam
- Fosphenytoin
- Frovatriptan
G
H
- Halothane
- Harmaline
- Harmine
- Hawaiian Baby Woodrose
- Hexedrone
- HHC
- Hydrochlorothiazide
- Hydrocodone
- Hydromorphone
- Hyoscyamine
- Hyoscyamus niger